Transcriptome analysis of the Vibrio fischeri LuxR-LuxI regulon.

نویسندگان

  • Luis Caetano M Antunes
  • Amy L Schaefer
  • Rosana B R Ferreira
  • Nan Qin
  • Ann M Stevens
  • Edward G Ruby
  • E Peter Greenberg
چکیده

The Vibrio fischeri quorum-sensing signal N-3-oxohexanoyl-l-homoserine lactone (3OC6-HSL) activates expression of the seven-gene luminescence operon. We used microarrays to unveil 18 additional 3OC6-HSL-controlled genes, 3 of which had been identified by other means previously. We show most of these genes are regulated by the 3OC6-HSL-responsive transcriptional regulator LuxR directly. This demonstrates that V. fischeri quorum sensing regulates a substantial number of genes other than those involved in light production.

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عنوان ژورنال:
  • Journal of bacteriology

دوره 189 22  شماره 

صفحات  -

تاریخ انتشار 2007